Named after the hundred-eyed watchman of Greek myth, Argus watches the education landscape: spotting new opportunities, pressure-testing the ventures we're building, and tracing every read back to the real-world signals behind it.
The evidence library: the raw signals the pipeline is watching across the education ecosystem. Every idea is built from these.
Scientists at the National Cancer Institute (NCI) have developed a novel tightly regulated drug-responsive, membrane-bound IL- 12 cytokine platform, that enhances anti-tumor efficacy in adoptive cell therapy (ACT) with engineered T-cells (CAR, TCR, TILs) while improving safety. The NCI seeks research co-development partners and/or licensees to advance this technology toward clinical translation.
The National Cancer Institute (NCI) seeks research co- development partners and/or licensees for a QPID digital autoradiography system with particle identification capabilities.
Scientists at the National Cancer Institute (NCI) have discovered a novel therapeutic, diagnostic and prognostic target for thrombosis: Soluble Tissue Factor (sTF). NCI has generated first-in- class antibodies and platform selectively neutralizing pathological coagulation while preserving normal hemostasis. This platform technology can be used to prevent, diagnose and treat pathological thrombosis caused by a variety of clinical conditions-including cancer, sepsis, infectious diseases (e.g., COVID), autoimmune disorders, trauma, heart conditions and inflammatory conditions. It offers a much more sensitive and specific test of thrombosis than the current D-dimer test. It may be applicable to any clinical condition which induces necroptosis, pyroptosis and NETtosis, such as cancer, neurodegenerative disease, ischemia-reperfusion and acute injuries, traumatic injuries, bacterial and viral infections, cardiovascular conditions, and atherosclerosis, inflammatory, autoimmune conditions, and
This technology encompasses a DNA methylation-based diagnostic platform designed to improve the accuracy and consistency of cancer classification, with demonstrated utility for tumors of the central nervous system, kidney, and hematopoietic system. By identifying disease-specific methylation signatures, the approach reduces interobserver variability and enhances diagnostic confidence. The central nervous system (CNS) classifier is built from a curated reference set of 16,567 methylation profiles and organizes tumors into 22 families and 133 clinically relevant diagnostic classes, including 21 newly developed methylation classes not represented in other existing tools. Across multiple independent validation cohorts (n = 5,875), the classifier demonstrated robust performance, and in a clinical-impact analysis of 1,204 NIH validation cases, methylation profiling materially influenced final diagnosis in 74.4% of cases by refining, increasing precision, or reclassifying. The CNS classifier
The National Cancer Institute (NCI) seeks research co- development partners and/or licensees to develop a collection of anti- CE1 antibodies for liver cancer treatment.
The National Cancer Institute (NCI) seeks research co- development partners and/or licensees for a novel monoclonal antibody (mAb), RO4, that can be used to treat mesothelin (MSLN) expressing cancers.
The National Cancer Institute, an institute of the National Institutes of Health, Department of Health and Human Services, is contemplating the grant of an Exclusive Patent License to practice the inventions embodied in the patents and patent applications listed in the Supplementary Information section of this notice to OptoSurgical LLC ("OptoSurgical"), a company located in Columbia, Maryland, the United States of America.
The National Cancer Institute (NCI) seeks licensees for a CRISPR/Cas9-engineered MC38 B2m knockout murine colon cancer cell line that models tumor resistance to PD-1/PD-L1 checkpoint blockade caused by loss of MHC-I antigen presentation. This research tool provides an opportunity to study checkpoint-refractory tumors and evaluate alternative or combination immunotherapy strategies for cancers that evade conventional T-cell-mediated recognition.
A few months ago I made a post about how I couldn't sleep because I was worried that I would never be a teacher again since I got a reprimand on my teacher certificate. I got a lot of hate including someone telling me that "my teaching days were over", but I now sit in front of you as a new teacher-of-record at a public school district. I had a number of schools tell me that my mark would bar me from being employed with them, but this district twenty-thirty minutes away from my home appreciated my honesty and saw that I had learned from my situation. There is hope for you if you are in a similar circumstance and want to continue teaching. You may have to send out a lot of applications, go to a lot of interviews, or be told that your sanction makes you ineligible for hire, but continue to be honest about your situation and let the interviewing panel know about your reprimand (I brought it up at the end of the interview after things went well). Hell, you might even be hired for your raw
a UK Biobank study says night shift workers show accelerated biological aging and lose almost a year of life expectancy. I feel sick to my stomach discovering this. submitted by /u/TheNzm7 [link] [comments]
Hi everyone, I’m starting my first year of teaching in about three weeks and I am wondering if you know the bare minimum things I would need in my classroom as a first grade teacher! For example, interchangeable Calendar IDK things like that! Thank you☺️☺️ submitted by /u/CalligrapherFine7986 [link] [comments]
I’ve been out sick for 2 days, and it’s about to be a 3rd but one of the nurses messaged me about my patient and said “***** passed away”. I get it’s my patient but at the same time… I’ll be back later this week. I’ll find out then. That’s not my concern right now. IM my concern right now. I understand that nurse is helping with my caseload but I didn’t reach out to that person when they were on vacation about their patients. I took on their caseload and updated them later. I hate how work follows you everywhere in this position. submitted by /u/consideredtaken [link] [comments]
The brown bag in the upper left corner is my SSRI + adhd meds LMAO. submitted by /u/Saelem [link] [comments]
I’m talking to you Bob and Tammy. You guys are “all talk” pretending to care about employees mental and physical health. You care more about sponsoring the sports teams and advertising how US News ranked you as a top hospital. You’re only as good as your employees and I hope there’s a mass exodus. You guys make millions and we barely make a living. submitted by /u/AlwaysWithTheOpinion [link] [comments]
Our school now does not want students to cut and paste. If I want the students to do a word sort and match pictures to terms, I have to cut it all out for them so they don’t waste instructional time cutting. This isn’t an exaggeration. If I want something cut I have to do it myself. Keep in mind, this is not for safety, it is for preserving instructional time. This is insane… right? submitted by /u/Goblinbooger [link] [comments]
my boyfriend recently became a teacher ! he’s having trouble with lunch though. there is a break room but it’s in a different building and his school is strange because he has a class and then the class goes on lunch break and then that same class comes right back. which leads to many students eating their lunch in his classroom so he can’t really leave the class. he’s essentially has been spamming uncrustables the past 2 weeks. though I know I have some decent quality ice packs so I’m thinking of starting to pack him something more nutritious but need ideas. much appreciated! submitted by /u/AdTimely7710 [link] [comments]
This year every school in the district has one or two or three "long-term subs," that they are using instead of hiring classroom teachers. I do not think this is because people are taking FMLA or anything, although I could be wrong. It's odd to me. Is this happening elsewhere? submitted by /u/OkayIsland [link] [comments]
My husband is absolutely gobsmacked that I’m not guaranteed a lunch every shift I work (ER) I told him that was kinda the national standard, so plz drop below if you ever get a lunch break lmao submitted by /u/carmelamacchiato [link] [comments]
Hi everyone, I work in a K-12 school and I teach high school. This year my own children will be in Kindergarten and second grade, and in order to save costs they will not be going to after school care and instead walking down to my room after school. Besides keeping a plethora of snacks on hand, does anyone have any tips to keep them entertained after school for about 30 minutes until my contract time is over? I teach high school and do not have toys in my room and kids are not allowed to be in the gym, running the halls, or outside on the playground. submitted by /u/corgimom28 [link] [comments]
Just passed the NCLEX and got my RN today. Do I get my own aesthetic or IV fluid clinic now? Do they automatically enroll me into an NP program? Or do I have to get my CRNA first? /s But yay for all of us new RNs! submitted by /u/Counselurrr [link] [comments]
I get that this post might be empty haha. submitted by /u/jensmith20055002 [link] [comments]
Has your hospital ever made a big mistake with a patient? Ours did recently, and it's bad...Wrong patient & procedure. Can't go into details, thank God had nothing to do with me or my unit! 😱 submitted by /u/DoItRightOnce1st [link] [comments]
So anyway, if y’all know of any job openings in a land far far away where I’d never see anyone ever again, pls lmk 🤧 submitted by /u/DirectionAcceptable9 [link] [comments]
I’m currently an oncology rn with over 1.5 years of experience, but I also recently got out of the crisis stabilization unit for admitting to my manager that I am suicidal after a patient passed and my brain was convincing me it was my fault. I spoke to the nurses in the unit who convinced me it wasn’t. And my manager and coworkers did as well. But my brain wasn’t accepting it. I felt better after being discharged for a little bit, but now every little thing is stressing me out and things I used to have confidence in addressing myself are things I’m freaking out about now. Yesterday a patients most recent potassium was 3.5. However out EMR flags it as low. Normal in the EMR is 3.6 to 5.0 for some reason. I asked a coworker to double check orders with me and she mentioned it. “Are they doing anything about the potassium?” And I was like, “I was always told 3.5 is normal” because that’s what I was taught in school. And she was just like “yeah ok.” And signed them. But I started spiraling
This nurse cared enough to report her local sheriff department to APS. When the sheriff claimed no wrong doing, she pushed the issue and fully documented the injuries. The patient, who was in a medical crisis for FIVE DAYS in a holding cell, lost his leg and is now permanently disabled. With the help of her extensive chart documentation, he’s now appropriately suing the sheriffs department. He was never arraigned or convicted of anything, neither. Excellent reminder to maintain accurate and consistent charting. 👍 submitted by /u/No_Knowledge4718 [link] [comments]
For those of us who worked through covid- and still feel the trauma of all that death. All the people we met and then watched die, or held an iPad in front of an intubated face with a sat of 40% and PEEP of 25 while listening to sobs from faces on the other side. Are any of you feeling the creeping sense of the memories and anger while reading the countless posts on SM "Yeah, I saw all your tick tock dances, you liars!". "Empty ICUs, empty hospital parking lots" like we are all collectively making up this huge conspiracy, and we didn't experience constant death. And I didn't hear the guttaral screams as a mother hit the floor while I crushed the chest of her 25 year old son, and the PA told her we had to stop? I know they are morons. They sat at home and listened to other morons tell them what their smooth brains wanted to hear via podcasts, SM, fox news or whatever they could find to placate their 6th grade mindset while we experienced what we did. I remember talking to my husband aft
Hey all, Seeking some advice here. I took a new job this year as a middle school PE teacher. This morning, a fight between two girls broke out during warmups and I stepped in between to break it up and ended up getting punched in the face. I know I shouldn’t step between them to protect myself now but that’s after the fact that I already did that. Anyway, I don’t super want to go back to teaching at this school anymore. Behaviors in addition to this are rough and I need to make sure I am in a safe environment. I’d like to speak with administration about letting me go without coming for my license so I can seek employment elsewhere. Does this sound reasonable? I don’t want to have the conversation and have it backfire on me. I’m currently at the workman’s comp waiting room to be checked out. In Illinois if it matters. Thanks for any advice submitted by /u/stairfact [link] [comments]
Waiting by the side door to the building in the stairwell for transportation to arrive with my students. Our school (urban, elementary) was three stories. Student walks in and begins his ascent. Halfway through the journey we hear “OH GOD I…I don’t think I’m going to make it… please… tell my wife… I love her…” submitted by /u/NjKareBear [link] [comments]
Sixth year teaching in this district. Far from the poorest school, generally done well financially. Apparently finances have been so low recently, that they have decided to take away control of thermostats for all buildings. They have set temperatures for us in the summer and winter, and I know it’s gonna be just the best goshdarn temperature ever. So how was your day? Edit: okay it never occurred to me that some places never had access to theirs 😬. Sorry about the shortsightedness! submitted by /u/composerv3 [link] [comments]
This may have somehow given an ounce of inspiration in the otherwise trodden down world of being a night shift nurse: A surgeon, of all people, who was trying to get my patient into the OR that night, had to cancel bc of some trauma (idk). So he told her it’s not happening. Great. Now, she hasn’t eaten in two days. I hadn’t addressed that yet. Well, he asked me about it and probably could tell it was pretty low on my priority list (it was shift change)… well, he goes down to the cafe and buys her dinner out of his own pocket and then came back up to the floor and hand delivered it. Wild. Nobody gets how wild that is. I have never ever seen that in my years. Anyway thought I’d share. submitted by /u/Avatar617 [link] [comments]
I wouldn't say I've been missing it Bob submitted by /u/Deranged-Pickle [link] [comments]
Good morning all. Just a general question. I’m 24 and am starting my 3rd school year teaching this year. I am also on my 3rd school building as well. In my experience, I’ve been one of 5 people or less in each school building I’ve worked in that were under the age of 40. I have also noticed that other new hires within the districts I’ve worked in for the most part are not younger people. I wonder if this is unique to my area, or if this is something that may be noticed widespread. What’s your thoughts? submitted by /u/Vast-State-4548 [link] [comments]
The nurses at work were reminiscing about the covid years, the volume of deaths, family members, the media, the pressure injuries on their faces from wearing masks, and just the sheer pressure on the healthcare system. A lot of the nurses voiced that they would leave the profession if there was another pandemic in their lifetime I joined nursing towards the end of the pandemic so I don’t have the raw experiences like many of you do Would you stay through another pandemic like covid? submitted by /u/No_Leading3793 [link] [comments]
Hi all Is anyone else using this Painchek thing at their facility? It's an AI video analysis that is meant to check if the non verbal person is in pain I seriously think it's a waste of money. I can't find any evidence it's better than the abbey pain scale either. I also learned they didn't test it on people who weren't white (?) submitted by /u/Outrageous_Fox_8796 [link] [comments]
I admitted a patient with stage 4 pancreatic cancer to med Surg for nausea, vomiting, abdominal pain. Fecal impaction was found. So the point was to enema and laxative our way through while controlling nausea and pain. Patient was female and in early 60s. We had a lot of good conversation. She spoke with a Connecticut accent like my mother in law, who I look up to. She carried a strong, don’t-feel-sorry-for-me attitude but it was combined with sarcasm and humor. Her hair was thin from chemo, her face, gaunt. I could see what a vibrant and beautiful person she’s been all her life. I enjoyed taking care of her. I came back the next night and she was not doing as well. Her husband and 2 sisters were there. They were lovely as well. The patient was still cracking her jokes, but the pain and heaving didn’t allow for as many. My meds weren’t working. Her family watched her like a hawk with fear and tears in their eyes holding it together, wondering if this time might be the last time they al
I am looking to go back to work after quite a few years off. I have experience in MedSurg/Tele, Neuro/Stroke, plastic surgery, and most recently pre-Covid school nursing. I do not want to go back to working in schools and I really don't want a stressful environment where people could die who are not supposed to die. That's why I was thinking about palliative care or hospice care. I'm also open to online telehealth nursing or things like that, did like end of care nursing. submitted by /u/UnluckyMarsupial9875 [link] [comments]
So I’m a new grad and take the nclex this month but since I’ve graduated a month ago and have more time on social media I see everyone and their mothers and fathers at this point is going into nursing ….ik the economy bad but damn I picked nursing right after high school I’m just scared it gets over saturated and pay goes down with ai and everything does anyone else feel the same ? Any OG nurses ? submitted by /u/Antique-Soft1292 [link] [comments]
I put my foot down today at a night shift nurse. I am a new hire at my job (1 month in) and i noticed this night shift RN interrupt a lot during bedside report even when i was shadowing my preceptors. IThis lady interrupts me after each sentence during bedside report. I snapped lol I hit her with the “please refrain from asking questions until after i give you the full report. Chances are, i will answer any question you may have during my report” Brooo she got so maaaaaaadd but idgaf I was nice too and professional Even smiled submitted by /u/JayLin95 [link] [comments]
I’m both a middle school teacher and a parent of school-age children. I started a part-time job a year ago in retail and was doing my onboarding training in August. The training covered a shooting scenario. In the retail setting, I was trained that my number one priority was myself. I was to do anything necessary to run, hide, or fight. I had absolutely no responsibility to the business, to the customers, or to any of my colleagues. I am to act in my own best interest with the priority to run. Juxtapose that with the beginning of school safety procedures. We are trained on lockdown protocols. But we are told that if we have the opportunity to run to take it. But as the classroom teacher, if I choose to run but not all of my students want to run with me, what is my liability? What is my professional responsibility? What is my ethical responsibility? My personal responsibility of parent to school-age children tells me to prioritize myself and do whatever I need to do to ensure I’m still
have a plan for how to get the medication left in the tubing into the patient. I'm not talking about fluids or the ED folks that hang the big ass 500 cc bag of vanco to gravity. I see people hang little 50 cc or 100 cc bags primary, through a pump, and then just run it dry because they don't think about the volume they used to prime the tubing. I was that fucking visitor today and touched an IV pump. I felt so shitty having to do it and only did so after having the call light on for a few minutes. They had hung 1 g methylprednisolone as a primary in a 50 cc bag and overprogrammed it by over 25 cc. It was the same tubing I use where I work and I know for a fact the primary and extension tubing they had on there was 20-25 cc depending on how full the drip chamber was. It had just started pulling air past the drip chamber so I hit the stop button. They had programmed it for the exact amount on the bag without a thought as to how to get the half to a third of the dose that was left in the
I’m in Australia and we only use brand names for a handful of meds. Where I work, these are typically Panadol, clexane, Movicol, buscopan, tazocin, augmentin, slow K/span K and a couple more my mind is blanking on. It’s hospital policy (and AFAIK legal policy) to use generic names to avoid confusion and keep everything standardised, but we let it slide for very common ones we all know. When I watch US medical shows (which is pretty much only The Pitt anyway) or stuff on social media, I’m always surprised at how many brand names are used. I’m constantly looking up meds I’ve never heard of only to find out it’s actually something I give every day. I remember watching The Pitt and being like “wtf is Ancef is that some niche antibiotic we never use” but turns out it’s just amoxicillin cefazolin. Doesn’t this cause confusion when there’s multiple brand names available? Are generic medications not as common over there so brand names end up being used more? Edit: by “we” in my first sentence
My district is back next week and I feel like messing with my 4th graders. Maybe I can convince them I’m psychic. I’m going to write a few predictions, seal them in envelopes or bags, and open them when the behavior happens. My ideas so far: 1- someone will need to go to the bathroom immediately upon hearing what my procedure is 2- someone will claim they can’t do PE because it will make their new shoes dirty (going to staple some bottles of shoe polish in paper bags for this one) 3- someone will need their phone out against school and district policy I know there are more annoying behaviors, but I had a nice summer and forgot about work. Any more ideas for me? submitted by /u/grumpy_apples [link] [comments]
one of my coworkers apparently is trying to sell our Nurses Week gift for three bucks. My husband got one too and washed it a few times and we now have a good laugh every time he breaks it out. submitted by /u/Emasinmancy [link] [comments]
Is it normal to be short in the ICU every shift? Our nurses are constantly tripled with charge always in staffing, we almost never have an aide, and also get floated on a very regular basis sometimes to the ER to take 6 med-tele holds. Is this how it is everywhere? I'm on Long Island and desperate for a new job but not having any luck...I don't want to leave a day shift ICU position but not sure how much more I can take. I have another 30-40 years of working and fear I'll lose my license here. submitted by /u/yell0wmacar0ni [link] [comments]
My district has a no cellphone in class policy. The language even says that students have to place the phone somewhere according to teacher instructions. I teach 8th and 9th grade and want zero phone usage, I’m very burnt out on telling students to put their phones away and want to begin “collecting” their phones every day. My question for yall is what methods do you have for collecting phones? I have a phone pocket chart but no where good to hang it. I have heard of some doing a pencil hard shell plastic case on the desk that students put their phones in but I’m not sure if I want to clutter their desk area (although I like the idea that their phone is still near them so they feel in control). What other options are there?? Thanks for your help! submitted by /u/Leather_Response_123 [link] [comments]
I’m curious. Hypothetically, if you use, let’s say 5 sick days and 2 personal days, just for days off, where are you using them? submitted by /u/Andromeada-dream [link] [comments]
I recently started learning the US at work for PIV starts/lab draws. While I’ve been a RN in my ICU for 2 years, I have very little experience with any pokes. I’m loosing my needle tip very often, but please share any and all tips and hacks you have learnt. I understand the best way to learn is by practice, so hopefully time will tell! submitted by /u/Open_Specific8415 [link] [comments]
This is my third year teaching 7th grade math. Teaching is my second career, so I have the unique position of being both middle aged and a new teacher at the same time. My background is in social work. I try not to fall back on the "back in my day..." comments, as middle school looks completely different than it did when I was a preteen and its just not helpful to compare modern times to the past. Too much has changed for it to be relevant. However, there are a few skills I've found to be surprisingly lacking in today's kids. The first is that at least 75% of my students don't know their times tables. They have an over reliance on calculators and so many things are more difficult if you haven't memorized basic multiplication. The vast majority can't read an analog clock. It might as well a sundial. They're just baffled. Perhaps the biggest challenge of all is the lack of critical thinking. Everything has to be fed to them and they absolutely refuse to struggle through anything. At the
The state of Florida has killed my spark. I can’t go teach anywhere else at the moment. I’m literally stuck here. Today was my first year with all ninth graders. I look very non-binary. I am non-binary but I can’t tell my students I’m non-binary because that’s illegal. I had many students who caught on to who I am or at least clocked who I am. And asked if I can call them by their preferred name. And I had to look these little freshman babies in the face and say no I cannot. I will get fired. If your name is not in the system that way and I get reported calling you your wrong name that’s not your first or last name that’s in the system I will lose my job. I also can’t have any non-approved books on the shelf. Now before it meant that if it wasn’t banned, I could have it on my bookshelf. But now, if it is not approved or band and a student says to their parent that they got it from my bookshelf (I don’t know how they will get proof, nobody knows actually) I will get fired and the parent
The Food and Drug Administration (FDA or we) is proposing to require the submission of generally recognized as safe (GRAS) notices for the use of a human or animal food substance purported to be GRAS under the conditions of its intended use under the Federal Food, Drug, and Cosmetic Act (FD&C Act).